Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.63 |
| ▸ | GPR52 | Q9Y2T5 | 13/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | TOP1 | P11387 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6758436 | 1.00 | KEAP1 (0.63) | KEAP1GPR52FFAR1HDAC3MAPK1 | |
| SCHEMBL7738555 | 1.00 | KEAP1 (0.63) | KEAP1GPR52FFAR1HDAC3MAPK1 | |
| SCHEMBL6758432 | 1.00 | KEAP1 (0.63) | KEAP1GPR52FFAR1HDAC3MAPK1 | |
| SCHEMBL6759998 | 1.00 | KEAP1 (0.63) | KEAP1GPR52FFAR1HDAC3MAPK1 | |
| SCHEMBL6759953 | 0.89 | FFAR1 (0.68) | KEAP1GPR52FFAR1SMN1; SMN2HDAC2 | |
| SCHEMBL6759945 | 0.89 | FFAR1 (0.68) | KEAP1GPR52FFAR1SMN1; SMN2HDAC2 | |
| SCHEMBL9671796 | 0.89 | HDAC3 (0.66) | KEAP1GPR52FFAR1HDAC3MAPK1 | |
| SCHEMBL2378147 | 0.89 | TOP1 (0.72) | KEAP1GPR52FFAR1HDAC3MAPK1 | |
| SCHEMBL9671802 | 0.89 | HDAC3 (0.66) | KEAP1GPR52FFAR1HDAC3MAPK1 | |
| SCHEMBL2378148 | 0.89 | TOP1 (0.72) | KEAP1GPR52FFAR1HDAC3MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002098220-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-12-12 | — | — | WO | disclosed |