Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 6/20 | 0.68 |
| ▸ | GPR52 | Q9Y2T5 | 5/20 | 0.58 |
| ▸ | MMP12 | P39900 | 5/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MMP13 | P45452 | 4/20 | 0.50 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6759953 | 1.00 | FFAR1 (0.68) | FFAR1GPR52MMP12FFAR4LMNA | |
| SCHEMBL7738555 | 0.89 | KEAP1 (0.63) | FFAR1GPR52KEAP1HDAC2SMN1; SMN2 | |
| SCHEMBL6758432 | 0.89 | KEAP1 (0.63) | FFAR1GPR52KEAP1HDAC2SMN1; SMN2 | |
| SCHEMBL7738550 | 0.89 | KEAP1 (0.63) | FFAR1GPR52KEAP1HDAC2SMN1; SMN2 | |
| SCHEMBL6759998 | 0.89 | KEAP1 (0.63) | FFAR1GPR52KEAP1HDAC2SMN1; SMN2 | |
| SCHEMBL6758436 | 0.89 | KEAP1 (0.63) | FFAR1GPR52KEAP1HDAC2SMN1; SMN2 | |
| SCHEMBL6756569 | 0.82 | CA2 (0.48) | FFAR1GPR52KEAP1 | |
| SCHEMBL6756571 | 0.82 | CA2 (0.48) | FFAR1GPR52KEAP1 | |
| SCHEMBL1211561 | 0.81 | FFAR1 (1.00) | FFAR1MMP12FFAR4LMNAABCC4 | |
| SCHEMBL8618654 | 0.81 | FFAR1 (1.00) | FFAR1MMP12FFAR4LMNAABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040034097-A1 | Pesticidal activity of functionalized alkenes | LINDERMAN RUSSELL J (US) | 2004-02-19 | — | — | US | claimed |
| US-20020193436-A1 | Pesticidal activity of functionalized alkenes | NORTH CAROLINA STATE UNIVERSITY | 2002-12-19 | — | — | US | claimed |
| WO-2002098220-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-12-12 | — | — | WO | claimed |
| US-6720450-B2 | USING SUCH AS 7-CYCLOHEXYL-(4,5-METHANO)HEPTANOIC ACID; CONTROLLING BLOOD INGESTING INSECTS | NORTH CAROLINA STATE UNIVERSITY | 2004-04-13 | — | — | US | disclosed |
| US-20040034097-A1 | Pesticidal activity of functionalized alkenes | LINDERMAN RUSSELL J (US) | 2004-02-19 | — | — | US | disclosed |
| US-6660770-B2 | Inhibit digestion by terminating or blocking synthesis of digestive enzymes by activating trypsin modulating oostatic factor receptor | NORTH CAROLINA STATE UNIVERSITY | 2003-12-09 | — | — | US | disclosed |
| US-20030149103-A1 | Pesticidal activity of functionalized cyclopropanes | NORTH CAROLINA STATE UNIVERSITY | 2003-08-07 | — | — | US | disclosed |
| WO-2003051118-A1 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED CYCLOPROPANES | NORTH CAROLINA STATE UNIVERSITY (US) | 2003-06-26 | — | — | WO | disclosed |
| US-20020193436-A1 | Pesticidal activity of functionalized alkenes | NORTH CAROLINA STATE UNIVERSITY | 2002-12-19 | — | — | US | disclosed |
| WO-2002098220-A2 | PESTICIDAL ACTIVITY OF FUNCTIONALIZED ALKENES | NORTH CAROLINA STATE UNIVERSITY (US) | 2002-12-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193436-A1 | Pesticidal activity of functionalized alkenes | VIP, ANPEP, APEH | FFAR1 369/4885GPR52 780/4885MMP12 1180/4885 |
| US-20040034097-A1 | Pesticidal activity of functionalized alkenes | VIP, ANPEP, APEH | FFAR1 369/4885GPR52 780/4885MMP12 1180/4885 |
| US-20030149103-A1 | Pesticidal activity of functionalized cyclopropanes | DDT, PPIF, CYP4F3 | FFAR1 3118/4885GPR52 2429/4885MMP12 1033/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.