Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741629 | 0.99 | NR3C2 (0.44) | NR3C2SMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL2900930 | 0.89 | PPARA (0.37) | SMN1; SMN2LMNAHTTKDM4EPOLB | |
| SCHEMBL2902275 | 0.87 | AR (0.39) | SMN1; SMN2LMNAHTTPOLBALDH1A1 | |
| SCHEMBL7738186 | 0.85 | NR3C2 (0.56) | NR3C2SMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL64769 | 0.85 | HTT (0.44) | SMN1; SMN2LMNAHTTALDH1A1CYP3A4 | |
| SCHEMBL65269 | 0.85 | HTT (0.44) | SMN1; SMN2LMNAHTTALDH1A1CYP3A4 | |
| SCHEMBL7733544 | 0.84 | NR3C2 (0.43) | NR3C2SMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL8319641 | 0.83 | HTT (0.35) | NR3C2SMN1; SMN2LMNAHTTPOLB | |
| SCHEMBL7741655 | 0.83 | NR3C2 (0.50) | NR3C2SMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL8320141 | 0.83 | PPARA (0.33) | SMN1; SMN2LMNAHTTPOLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416928-B1 | HALOGENONIUM OR SULFONIUM SALTS OF SULFONATED DIPHENYLALKANE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2002-07-09 | — | — | US | disclosed |