Known targets — ChEMBL curated mechanism
FGFR1FGFR2FGFR3FGFR4FLT1FLT4KDRPDGFRAPDGFRB
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.32 |
| ▸ | MMP2 | P08253 | 3/20 | 0.32 |
| ▸ | MMP13 | P45452 | 3/20 | 0.32 |
| ▸ | PPARA | Q07869 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | MMP1 | P03956 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8317869 | 0.92 | PABPC1 (0.33) | HTTLMNAALDH1A1CNR2KMT2A | |
| SCHEMBL8320141 | 0.91 | PPARA (0.33) | HTTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8316981 | 0.91 | PPARA (0.33) | HTTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL2900930 | 0.88 | PPARA (0.37) | HTTLMNAALDH1A1KMT2AMEN1 | |
| SCHEMBL8646729 | 0.88 | CETP (0.33) | ALDH1A1CNR2KMT2AABCB1MMP2 | |
| SCHEMBL8651814 | 0.88 | CETP (0.33) | ALDH1A1CNR2KMT2AABCB1MMP2 | |
| SCHEMBL8317614 | 0.87 | PPARG (0.33) | HTTLMNAMMP2MMP13PPARA | |
| SCHEMBL2903862 | 0.87 | PABPC1 (0.36) | ALDH1A1MMP13PPARAPPARGCA12 | |
| Trifluoromethanesulfonic Acid SCHEMBL64048 | 0.87 | GPR3 (0.37) | CNR2PPARAKIF11 | |
| Trifluoromethanesulfonic Acid SCHEMBL63998 | 0.87 | GPR3 (0.37) | CNR2PPARAKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5880169-A | HAVING HIGH RESOLUTION FOR FINE PATTERNING | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1999-03-09 | — | — | US | disclosed |