Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 8/20 | 0.60 |
| ▸ | TSHR | P16473 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6931822 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL6560872 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL27388817 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL29037417 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL6560567 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL2729006 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL8817484 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL29219544 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL2233453 | 1.00 | DNM1 (0.60) | DNM1TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL6558516 | 0.97 | DNM1 (0.55) | DNM1TSHRMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160008297-A1 | COMPOUNDS FOR PREVENTING, REDUCING AND/OR ALLEVIATING ITCHY SKIN CONDITION(S) | B.R.A.I.N. BIOTECHNOLOGY RESEARCH AND INFORMATION NETWORK AG (DE) | 2016-01-14 | — | — | US | disclosed |
| US-6417146-B1 | LIQUID DETERGENTS OF SURFACTANT BLEND | KAO CORPORATION (JP) | 2002-07-09 | — | — | US | disclosed |
| WO-2000042156-A9 | DETERGENT COMPOSITIONS COMPRISING A PECTATE LYASE AND A BLEACH SYSTEM | PROCTER & GAMBLE (US) | 2001-06-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160008297-A1 | COMPOUNDS FOR PREVENTING, REDUCING AND/OR ALLEVIATING ITCHY SKIN CONDITION(S) | TRPV2, TRPV1, TRPM2 | DNM1 4022/4885TSHR 3199/4885MEN1 2754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.