SCHEMBL4381001

SCHEMBL4381001

O=C(O)C1CCCC(Cl)(C(=O)O)C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.46
TSHR P16473 3/20 0.46
GRM2 Q14416 2/20 0.46
GRM3 Q14832 2/20 0.46
GRM4 Q14833 2/20 0.46
CYP2C19 P33261 2/20 0.46
ALOX15 P16050 2/20 0.46
LMNA P02545 2/20 0.46
TDP1 Q9NUW8 1/20 0.46
GRM8 O00222 1/20 0.46
GRM6 O15303 1/20 0.46
GRM5 P41594 1/20 0.46
MTOR P42345 1/20 0.46
GRM1 Q13255 1/20 0.46
PLCB1 Q9NQ66 1/20 0.46
SLC6A3 Q01959 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
SLC6A4 P31645 1/20 0.36
APLNR P35414 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4372279 0.88 GRM4 (0.53) CYP1A2TSHRGRM2GRM3GRM4
SCHEMBL6520915 0.79 ARG1 (0.34) CYP1A2TSHRGRM2GRM3GRM4
SCHEMBL3580152 0.79 ARG1 (0.34) CYP1A2TSHRGRM2GRM3GRM4
SCHEMBL4264841 0.79 ARG1 (0.34) CYP1A2TSHRGRM2GRM3GRM4
SCHEMBL4380991 0.78 CYP2C19 (0.55) CYP1A2TSHRGRM2GRM3GRM4
SCHEMBL3581158 0.78 TSHR (0.42) CYP1A2TSHRGRM2GRM3GRM4
SCHEMBL4184713 0.75 CYP1A2 (0.48) CYP1A2TSHRGRM2GRM3GRM4
SCHEMBL895276 0.74 GRM2 (0.47) CYP1A2TSHRGRM2GRM3GRM4
SCHEMBL7739044 0.74 SLC6A4 (0.45) CYP1A2TSHRGRM2GRM3GRM4
SCHEMBL4991380 0.72 CYP2C19 (0.54) CYP1A2TSHRGRM2GRM3GRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118142347-A Preparation method of aliphatic positive nanofiltration membrane based on polyamine diacid chloride monomer 中国石油大学(华东) 2024-06-07 CN claimed
CN-118142347-A Preparation method of aliphatic positive nanofiltration membrane based on polyamine diacid chloride monomer 中国石油大学(华东) 2024-06-07 CN disclosed
CN-116802774-A Hollow microsphere 株式会社德山 2023-09-22 CN disclosed
EP-3476592-B1 MULTILAYER FILM TORAY INDUSTRIES (JP) 2023-06-14 EP disclosed
CN-109311287-B Laminated film 东丽株式会社 2021-08-24 CN disclosed
US-20210139390-A1 PRODUCTION METHOD OF ORGANIC COMPOUND UNITIKA LTD. (JP) 2021-05-13 US disclosed
EP-3819283-A1 METHOD FOR PRODUCING ORGANIC COMPOUND Unitika Ltd. (JP) 2021-05-12 EP disclosed
CN-112384489-A Method for producing organic compound 尤尼吉可株式会社 2021-02-19 CN disclosed
US-10751980-B2 Multilayer film TORAY INDUSTRIES, INC. (JP) 2020-08-25 US disclosed
US-20190217587-A1 MULTILAYER FILM TORAY INDUSTRIES, INC. (JP) 2019-07-18 US disclosed
EP-1179556-A1 BRANCHED AROMATIC POLYCARBONATE, PROCESS FOR PRODUCING THE SAME, AND BLOW-MOLDED ARTICLE THEREOF TEIJIN LIMITED (JP) 2002-02-13 EP disclosed
EP-1116751-A1 POLYCARBONATE RESIN COMPOSITION, OPTICAL RECORDING MEDIUM, AND SUBSTRATE THEREFOR TEIJIN LIMITED (JP) 2001-07-18 EP disclosed
EP-0736561-A2 Dihydroxy compound mixtures and polymers thereof GENERAL ELECTRIC COMPANY (US) 1996-10-09 EP disclosed
EP-0036629-B1 MELT PROCESSABLE POLY(ESTER CARBONATE) WITH HIGH GLASS TRANSITION TEMPERATURE ALLIED CORPORATION (US) 1984-08-08 EP disclosed
EP-0017740-B1 PREPARATION OF POLY(ESTER CARBONATE) BY INTERFACIAL METHOD ALLIED CORPORATION (US) 1984-04-25 EP disclosed
US-4310652-A Melt processable poly(ester carbonate) with high glass transition temperature ALLIED CHEMICAL CORPORATION (US) 1982-01-12 US disclosed
EP-0036629-A1 Melt processable poly(ester carbonate) with high glass transition temperature ALLIED CORPORATION (US) 1981-09-30 EP disclosed
EP-0027844-A1 Poly(ester carbonate) with high glass transition temperature ALLIED CORPORATION (US) 1981-05-06 EP disclosed
US-4255556-A Preparation of poly(ester carbonate) by interfacial method ALLIED CHEMICAL CORPORATION (US) 1981-03-10 US disclosed
EP-0017740-A1 Preparation of poly(ester carbonate) by interfacial method ALLIED CORPORATION (US) 1980-10-29 EP disclosed