Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | NOS3 | P29474 | 3/20 | 0.38 |
| ▸ | NOS1 | P29475 | 3/20 | 0.38 |
| ▸ | NOS2 | P35228 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.37 |
| ▸ | MDM4 | O15151 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738397 | 0.90 | NR1H2 (0.38) | L3MBTL1KMT2ANR1H2NR1H3 | |
| SCHEMBL7738409 | 0.83 | NOS2 (0.43) | ATML3MBTL1KMT2AALDH1A1POLB | |
| SCHEMBL7738402 | 0.83 | NOS2 (0.43) | ATML3MBTL1KMT2AALDH1A1POLB | |
| SCHEMBL7739221 | 0.82 | ATM (0.33) | ATML3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7740832 | 0.80 | ATM (0.36) | ATML3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL7739238 | 0.77 | SMN1; SMN2 (0.47) | ALDH1A1TSHR | |
| SCHEMBL7740834 | 0.75 | ACE (0.53) | — | |
| SCHEMBL20240304 | 0.73 | ATM (0.55) | ATML3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL20240285 | 0.70 | CTSS (0.50) | ATML3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL1430082 | 0.69 | KLK5 (0.54) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |
| WO-2000049022-A2 | ORGANOSILICON COMPOUNDS AND USES THEREOF | NORTHWESTERN UNIVERSITY (US) | 2000-08-24 | — | — | WO | disclosed |