Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | TACR3 | P29371 | 1/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738440 | 0.86 | TACR1 (0.46) | KMT2AMEN1ALDH1A1LMNATACR1 | |
| SCHEMBL7738442 | 0.86 | TACR1 (0.46) | KMT2AMEN1ALDH1A1LMNATACR1 | |
| SCHEMBL7739255 | 0.80 | ATM (0.41) | ATMKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7739221 | 0.77 | ATM (0.33) | ATMKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7738397 | 0.75 | NR1H2 (0.38) | KMT2AL3MBTL1 | |
| SCHEMBL20240283 | 0.70 | KMT2A (0.58) | ATMKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL20240285 | 0.65 | CTSS (0.50) | ATMKMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL7738441 | 0.64 | AKR1B1 (0.32) | ALDH1A1TACR1 | |
| SCHEMBL7738409 | 0.64 | NOS2 (0.43) | ATMKMT2AALDH1A1TACR1L3MBTL1 | |
| SCHEMBL7738402 | 0.64 | NOS2 (0.43) | ATMKMT2AALDH1A1TACR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6416861-B1 | COMBINATORIAL CHEMISTRY | NORTHWESTERN UNIVERSITY | 2002-07-09 | — | — | US | disclosed |