SCHEMBL7739261

SCHEMBL7739261

O=C1c2ccccc2C(=O)c2c(CC3[CH]CCCC3)cccc21

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.39
L3MBTL1 Q9Y468 6/20 0.39
MAPK1 P28482 5/20 0.39
ALDH1A1 P00352 4/20 0.39
EGFR P00533 4/20 0.39
RAF1 P04049 1/20 0.39
ALOX12 P18054 1/20 0.39
MAP2K1 Q02750 1/20 0.39
ADORA2A P29274 1/20 0.38
LMNA P02545 4/20 0.38
HPGD P15428 2/20 0.36
TDP1 Q9NUW8 4/20 0.36
PABPC1 P11940 2/20 0.36
RAB9A P51151 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
NSD2 O96028 1/20 0.36
KMT2A Q03164 4/20 0.35
MEN1 O00255 3/20 0.35
MAOA P21397 2/20 0.35
PTPN1 P18031 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7738544 0.99 MAPT (0.40) MAPTL3MBTL1MAPK1ALDH1A1EGFR
SCHEMBL7738515 0.99 MAPT (0.40) MAPTL3MBTL1MAPK1ALDH1A1EGFR
SCHEMBL7737941 0.99 MAPT (0.40) MAPTL3MBTL1MAPK1ALDH1A1EGFR
SCHEMBL7737740 0.99 MAPT (0.40) MAPTL3MBTL1MAPK1ALDH1A1EGFR
SCHEMBL7739394 0.96 MAPT (0.40) MAPTL3MBTL1MAPK1ALDH1A1EGFR
Bromide SCHEMBL8560844 0.73 POLB (0.49) MAPTL3MBTL1MAPK1ALDH1A1EGFR
SCHEMBL2397166 0.69 ALDH1A1 (0.43) MAPTL3MBTL1MAPK1ALDH1A1EGFR
SCHEMBL83136 0.68 ADORA2A (0.53) MAPTL3MBTL1MAPK1ALDH1A1EGFR
SCHEMBL9213962 0.68 ADORA2A (0.53) MAPTL3MBTL1MAPK1ALDH1A1EGFR
SCHEMBL7732758 0.68 ATM (0.35) MAPTALDH1A1HPGDKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410748-B1 Alicycli c group-containing monomer KABUSHIKI KAISHA TOSHIBA (JP) 2002-06-25 US disclosed
US-6291129-B1 LIGHT SENSITIVE ELEMENT WITH UNSATURATED POLYMERS KABUSHIKI KAISHA TOSHIBA (JP) 2001-09-18 US disclosed