Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CASR | P41180 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11357210 | 0.87 | MMP8 (0.46) | MMP8MEN1KMT2ANPC1PIN1 | |
| SCHEMBL4859412 | 0.86 | KMT2A (0.50) | MEN1KMT2ASLC6A3TSHR | |
| SCHEMBL6535530 | 0.85 | ALDH1A1 (0.43) | MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL11442350 | 0.85 | ALDH1A1 (0.38) | MEN1KMT2ANPC1SMN1; SMN2GAA | |
| SCHEMBL7374272 | 0.82 | MMP8 (0.53) | MMP8MEN1KMT2ANPC1PIN1 | |
| SCHEMBL10677671 | 0.82 | MMP8 (0.42) | MMP8MEN1KMT2ANPC1PIN1 | |
| SCHEMBL10342626 | 0.81 | MMP8 (0.49) | MMP8MEN1KMT2ANPC1PIN1 | |
| SCHEMBL17396664 | 0.81 | EPHX1 (0.42) | MEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL10682628 | 0.80 | MMP8 (0.40) | MMP8MEN1KMT2ANPC1SMN1; SMN2 | |
| SCHEMBL10676619 | 0.80 | MMP8 (0.40) | MMP8MEN1KMT2ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002076940-A2 | PROCESS FOR PREPARING ARYLPIPERIDINE CARBINOL INTERMEDIATES AND DERIVATIVES | PENTECH PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |
| EP-1124802-A1 | PROCESS FOR PRODUCING 4-ARYLPIPERIDINE-3-CARBINOLS AND RELATED COMPOUNDS | Synthon B.V. (NL) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026187-A1 | PROCESS FOR PRODUCING 4-ARYLPIPERIDINE-3-CARBINOLS AND RELATED COMPOUNDS | SYNTHON B.V. (NL) | 2000-05-11 | — | — | WO | disclosed |