Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALPG | P10696 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11442350 | 0.86 | ALDH1A1 (0.38) | ALDH1A1LMNASMN1; SMN2MAPTKMT2A | |
| SCHEMBL7739376 | 0.85 | MMP8 (0.47) | SMN1; SMN2KMT2AMEN1GAA | |
| SCHEMBL7737117 | 0.80 | SMN1; SMN2 (0.46) | ALDH1A1LMNASMN1; SMN2TDP1ALPG | |
| SCHEMBL28269367 | 0.80 | EPHX2 (0.41) | ALDH1A1LMNASMN1; SMN2TDP1MAPT | |
| Hydrochloric Acid SCHEMBL7775055 | 0.77 | MAPT (0.40) | ALDH1A1LMNASMN1; SMN2TDP1MAPT | |
| SCHEMBL360667 | 0.76 | SMN1; SMN2 (0.51) | ALDH1A1LMNASMN1; SMN2TDP1MAPT | |
| SCHEMBL17396664 | 0.76 | EPHX1 (0.42) | ALDH1A1SMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL6576846 | 0.74 | SMN1; SMN2 (0.44) | ALDH1A1LMNASMN1; SMN2TDP1MAPT | |
| SCHEMBL8423984 | 0.74 | SMN1; SMN2 (0.46) | ALDH1A1LMNASMN1; SMN2TDP1MAPT | |
| SCHEMBL11336684 | 0.74 | SLC2A1 (0.38) | ALDH1A1LMNASMN1; SMN2TDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010053862-A1 | Process for preparing arylpiperidine carbinol intermediates and derivatives | PENTECH PHARMACEUTICALS, INC. | 2001-12-20 | — | — | US | claimed |
| EP-1140832-A4 | PROCESS FOR PREPARING ARYLPIPERIDINE CARBINOL INTERMEDIATES AND DERIVATIVES | PENTECH PHARMACEUTICALS INC (US) | 2004-11-03 | — | — | EP | disclosed |
| WO-2002076940-A2 | PROCESS FOR PREPARING ARYLPIPERIDINE CARBINOL INTERMEDIATES AND DERIVATIVES | PENTECH PHARMACEUTICALS, INC. (US) | 2002-10-03 | — | — | WO | disclosed |
| US-20010053862-A1 | Process for preparing arylpiperidine carbinol intermediates and derivatives | PENTECH PHARMACEUTICALS, INC. | 2001-12-20 | — | — | US | disclosed |
| EP-1140832-A1 | PROCESS FOR PREPARING ARYLPIPERIDINE CARBINOL INTERMEDIATES AND DERIVATIVES | PENTECH PHARMACEUTICALS, INC. (US) | 2001-10-10 | — | — | EP | disclosed |
| EP-1124802-A1 | PROCESS FOR PRODUCING 4-ARYLPIPERIDINE-3-CARBINOLS AND RELATED COMPOUNDS | Synthon B.V. (NL) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000037443-A1 | PROCESS FOR PREPARING ARYLPIPERIDINE CARBINOL INTERMEDIATES AND DERIVATIVES | PENTECH PHARMACEUTICALS, INC. (US) | 2000-06-29 | — | — | WO | disclosed |
| WO-2000026187-A1 | PROCESS FOR PRODUCING 4-ARYLPIPERIDINE-3-CARBINOLS AND RELATED COMPOUNDS | SYNTHON B.V. (NL) | 2000-05-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010053862-A1 | Process for preparing arylpiperidine carbinol intermediates and derivatives | ADH1C, CBR1, MAL2 | ALDH1A1 76/4885LMNA 574/4885SMN1; SMN2 4562/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.