Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.37 |
| ▸ | PTGIR | P43119 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 7/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.35 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7730072 | 0.94 | S1PR5 (0.38) | KDM4EMEN1POLBMAPTKMT2A | |
| SCHEMBL7737060 | 0.82 | ADRA1B (0.36) | MEN1KMT2APPARGPPARACHRM2 | |
| SCHEMBL7730171 | 0.81 | PTGIR (0.48) | POLBMAPTTBXA2RPTGIRPPARG | |
| SCHEMBL7729885 | 0.80 | KDM4E (0.39) | KDM4EMEN1POLBMAPTKMT2A | |
| SCHEMBL7730044 | 0.78 | PTGIR (0.48) | TBXA2RPTGIRPPARGPPARAALDH1A1 | |
| SCHEMBL7729838 | 0.76 | PTGIR (0.47) | POLBMAPTTBXA2RPTGIRPPARG | |
| SCHEMBL7730050 | 0.75 | TBXA2R (0.38) | KMT2ATBXA2RPTGIRPTGER1PTGER4 | |
| SCHEMBL7739691 | 0.74 | S1PR5 (0.39) | KDM4EMEN1POLBMAPTKMT2A | |
| SCHEMBL7737711 | 0.73 | HRH3 (0.41) | POLBMAPTTBXA2RPTGIRPPARG | |
| SCHEMBL7739735 | 0.73 | HTR1A (0.39) | MEN1KMT2ATBXA2RPTGIRCHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1028113-A1 | FUSED BENZENE HETEROCYCLE DERIVATIVES AND UTILIZATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-08-16 | — | — | EP | disclosed |