Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.39 |
| ▸ | HTR1D | P28221 | 5/20 | 0.39 |
| ▸ | HTR1B | P28222 | 5/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | NMT1 | P30419 | 3/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | PTGIR | P43119 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMO | O15229 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7737686 | 0.91 | ALDH1A1 (0.39) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| SCHEMBL7737346 | 0.82 | PTGIR (0.49) | TBXA2RPTGIRALDH1A1MEN1KMT2A | |
| SCHEMBL7739672 | 0.73 | KDM4E (0.38) | TBXA2RPTGIRALDH1A1MEN1KMT2A | |
| SCHEMBL7730050 | 0.72 | TBXA2R (0.38) | TBXA2RPTGIRKMT2A | |
| SCHEMBL7739662 | 0.71 | TBXA2R (0.39) | TBXA2RPTGIR | |
| SCHEMBL7736480 | 0.70 | ALDH1A1 (0.41) | HTR1AHTR1DHTR1BSLC6A4KCNH2 | |
| SCHEMBL7737376 | 0.68 | TBXA2R (0.48) | TBXA2RPTGIRALDH1A1 | |
| SCHEMBL7730072 | 0.67 | S1PR5 (0.38) | TBXA2RPTGIRALDH1A1MEN1KMT2A | |
| SCHEMBL7737236 | 0.67 | TBXA2R (0.48) | TBXA2RPTGIRALDH1A1 | |
| SCHEMBL4973366 | 0.67 | KMO (0.49) | ALDH1A1KMOMEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407096-B1 | 1,4-BENZOTHIAZINE AND 1,4-BENZOXAZINE DERIVATIVES; HYPOTENSIVE, ANTIISCHEMIC, ANTIALLERGEN, ANTIASTHMATIC AND ANTICOAGULANT AGENTS; CARDIOVASCULAR DISORDERS | TORAY INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1028113-A1 | FUSED BENZENE HETEROCYCLE DERIVATIVES AND UTILIZATION THEREOF | TORAY INDUSTRIES, INC. (JP) | 2000-08-16 | — | — | EP | disclosed |