SCHEMBL7739852

SCHEMBL7739852

O=C(OCCc1ccccc1OC(=O)c1ccc(O)cc1)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.62
ESR2 Q92731 4/20 0.62
LMNA P02545 3/20 0.51
NPSR1 Q6W5P4 2/20 0.51
SMN1; SMN2 Q16637 4/20 0.50
MAPT P10636 3/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
TDP1 Q9NUW8 3/20 0.49
TSHR P16473 2/20 0.49
SLC6A2 P23975 2/20 0.49
ALDH1A1 P00352 1/20 0.49
CHRM1 P11229 1/20 0.49
KDR P35968 1/20 0.49
TYR P14679 2/20 0.48
KMT2A Q03164 4/20 0.47
MEN1 O00255 2/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL891145 0.87 LMNA (0.59) ESR1ESR2LMNANPSR1SMN1; SMN2
SCHEMBL5152874 0.83 ESR1 (0.80) ESR1ESR2LMNASMN1; SMN2MAPT
SCHEMBL6536760 0.83 NPSR1 (0.46) ESR1ESR2LMNANPSR1SMN1; SMN2
SCHEMBL7759505 0.81 ESR1 (0.54) ESR1ESR2LMNANPSR1SMN1; SMN2
SCHEMBL4907924 0.80 ESR1 (0.66) ESR1ESR2LMNASMN1; SMN2MAPT
SCHEMBL5162031 0.80 KMT2A (0.63) ESR1ESR2LMNANPSR1SMN1; SMN2
SCHEMBL28324732 0.80 LMNA (0.56) ESR1ESR2LMNASMN1; SMN2MAPT
SCHEMBL6281235 0.80 THRB (0.51) ESR1ESR2LMNANPSR1SMN1; SMN2
SCHEMBL10919965 0.79 ESR1 (0.51) ESR1ESR2LMNANPSR1SMN1; SMN2
SCHEMBL30629783 0.79 NPSR1 (0.59) ESR1ESR2LMNANPSR1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6410479-B1 PRINTABILITY AND SURFACE GLOSS; FORMED BY COATING ON A PAPER SUBSTRATE A LAYER CONTAINING INORGANIC PIGMENTS AND A FIXING COMPOSITION OF A WATER SOLUBLE POLYMER OR RESIN WHICH DOES NOT CAUSE STICKING NIPPON PAPER INDUSTRIES CO LTD (JP) 2002-06-25 US disclosed
US-6284706-B1 COLOR DEVELOPMENT LAYER ON SUBSTRATE NIPPON PAPER INDUSTRIES CO LTD (JP) 2001-09-04 US disclosed
US-6284707-B1 MIXTURE OF BLUE LEUCO DYE AND BLACK LEUCO DYE NOPON PAPER INDUSTRIES CO LTD (JP) 2001-09-04 US disclosed
EP-1053888-A1 A thermally sensitive recording paper NIPPON PAPER INDUSTRIES CO., LTD. (JP) 2000-11-22 EP disclosed