Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.44 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4901578 | 0.89 | TSHR (0.54) | ESR1ESR2NPSR1HSD17B10ALDH1A1 | |
| SCHEMBL4846409 | 0.84 | ESR1 (0.69) | ESR1ESR2NPSR1HSD17B10ALDH1A1 | |
| SCHEMBL7739852 | 0.81 | ESR1 (0.62) | ESR1ESR2NPSR1HSD17B10ALDH1A1 | |
| SCHEMBL4907924 | 0.80 | ESR1 (0.66) | ESR1ESR2ALDH1A1TSHRFOLH1 | |
| SCHEMBL10919965 | 0.79 | ESR1 (0.51) | ESR1ESR2NPSR1HSD17B10ALDH1A1 | |
| SCHEMBL30629783 | 0.79 | NPSR1 (0.59) | ESR1ESR2NPSR1HSD17B10ALDH1A1 | |
| SCHEMBL891145 | 0.78 | LMNA (0.59) | ESR1ESR2NPSR1HSD17B10ALDH1A1 | |
| Ethylbenzene SCHEMBL8778067 | 0.78 | ESR1 (0.57) | ESR1ESR2HSD17B10ALDH1A1KDM4E | |
| SCHEMBL4904703 | 0.78 | ESR1 (0.58) | ESR1ESR2ALDH1A1TSHRFOLH1 | |
| SCHEMBL8778062 | 0.77 | ESR1 (0.51) | ESR1ESR2HSD17B10ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0778157-B1 | A thermal recording medium | JUJO PAPER CO LTD (JP) | 2001-04-04 | — | — | EP | disclosed |
| US-5811368-A | BASIC LEUCO DYE, PHENOLIC COLOR DEVELOPER; IMPROVED STABILITY TO PLASTICIZERS | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1998-09-22 | — | — | US | disclosed |
| EP-0778157-A2 | A thermal recording medium | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1997-06-11 | — | — | EP | disclosed |