Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 4/20 | 0.41 |
| ▸ | EDNRA | P25101 | 4/20 | 0.41 |
| ▸ | TAS2R31 | P59538 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | PLK1 | P53350 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29500460 | 0.78 | RIPK1 (0.53) | EDNRBEDNRATAS2R31GAAMAPT | |
| SCHEMBL28763488 | 0.74 | GAA (0.40) | EDNRBEDNRAGAAMAPTMEN1 | |
| SCHEMBL27660446 | 0.73 | MAPT (0.43) | EDNRBEDNRAGAAMAPTMEN1 | |
| SCHEMBL27660508 | 0.71 | MEN1 (0.51) | EDNRBEDNRAGAAMAPTMEN1 | |
| SCHEMBL11109058 | 0.69 | MEN1 (0.41) | EDNRBEDNRAGAAMAPTMEN1 | |
| SCHEMBL28524099 | 0.69 | STK17B (0.36) | GAAMAPTMEN1KMT2ANPSR1 | |
| SCHEMBL27867200 | 0.69 | NPC1 (0.38) | EDNRBEDNRAGAAMAPTMEN1 | |
| SCHEMBL8577388 | 0.68 | GAA (0.39) | TAS2R31GAAMAPTMEN1KMT2A | |
| SCHEMBL8574170 | 0.68 | GAA (0.39) | TAS2R31GAAMAPTMEN1KMT2A | |
| SCHEMBL27680435 | 0.68 | MAPT (0.38) | EDNRBEDNRAGAAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001003687-A2 | METHOD AND COMPOSITIONS FOR INHIBITING BIOSYNTHESIS OR BIOACTIVITY OF ENDOGENOUS STEROID SEX HORMONES IN HUMANS | CEDARS-SINAI MEDICAL CENTER (US) | 2001-01-18 | — | — | WO | claimed |
| WO-2001003687-A2 | METHOD AND COMPOSITIONS FOR INHIBITING BIOSYNTHESIS OR BIOACTIVITY OF ENDOGENOUS STEROID SEX HORMONES IN HUMANS | CEDARS-SINAI MEDICAL CENTER (US) | 2001-01-18 | — | — | WO | disclosed |