Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GABRP | O00591 | 2/20 | 0.33 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | GABRE | P78334 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18343704 | 0.84 | BTK (0.43) | ALDH1A1KMT2AMEN1TSHRTDP1 | |
| SCHEMBL14822490 | 0.80 | HCAR2 (0.43) | ALDH1A1KMT2AMEN1TSHRTDP1 | |
| SCHEMBL28987726 | 0.78 | MEN1 (0.35) | ALDH1A1KMT2AMEN1TSHRTDP1 | |
| SCHEMBL7740030 | 0.76 | HCAR2 (0.45) | ALDH1A1KMT2AMEN1TSHRTDP1 | |
| SCHEMBL2324062 | 0.75 | ALDH1A1 (0.67) | ALDH1A1KMT2AMEN1TSHRKDM4E | |
| SCHEMBL2089718 | 0.73 | TDP1 (0.32) | ALDH1A1KMT2AMEN1TSHRTDP1 | |
| SCHEMBL358337 | 0.72 | — | — | |
| SCHEMBL2364837 | 0.72 | CYP3A4 (0.49) | ALDH1A1KMT2AMEN1TSHRKDM4E | |
| SCHEMBL27958473 | 0.71 | MEN1 (0.35) | ALDH1A1KMT2AMEN1TSHRTDP1 | |
| SCHEMBL5134164 | 0.70 | IL1B (0.45) | ALDH1A1KMT2AMEN1TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2144898-B1 | HETEROCYCLIC HYDRAZIDE COMPOUND AND PESTICIDAL USE OF THE SAME | SUMITOMO CHEMICAL CO (JP) | 2012-02-08 | — | — | EP | disclosed |
| EP-0151866-A2 | Herbicidal pyrazole-(thio)-carboxamides | ELI LILLY AND COMPANY (US) | 1985-08-21 | — | — | EP | disclosed |