Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.34 |
| ▸ | METTL3 | Q86U44 | 1/20 | 0.34 |
| ▸ | METTL14 | Q9HCE5 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | AHR | P35869 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738267 | 0.88 | POLB (0.35) | AKR1B1MIFLOXL2GSK3BIDO1 | |
| SCHEMBL7738327 | 0.75 | AKR1B1 (0.38) | AKR1B1MIFLOXL2GSK3BNLRP3 | |
| SCHEMBL28840291 | 0.73 | LOXL2 (0.47) | LOXL2HRH3AHRHRH4MTNR1A | |
| SCHEMBL7738288 | 0.71 | — | — | |
| Ethylamine SCHEMBL7808639 | 0.69 | LOXL2 (0.50) | LOXL2AHRHRH4MTNR1AMTNR1B | |
| Sulfuric Acid SCHEMBL8528614 | 0.67 | LOXL2 (0.43) | LOXL2AHRMTNR1AMTNR1BGUSB | |
| SCHEMBL7731325 | 0.65 | TBXAS1 (0.35) | AKR1B1MIFLOXL2GSK3BIDO1 | |
| SCHEMBL3451201 | 0.62 | LOXL2 (0.58) | AKR1B1LOXL2GSK3BNLRP3IDO1 | |
| SCHEMBL9027547 | 0.62 | LOXL2 (0.58) | LOXL2NLRP3HRH3AHROPRK1 | |
| SCHEMBL31336079 | 0.61 | LOXL2 (0.56) | AKR1B1LOXL2GSK3BNLRP3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37781-E1 | VIRICIDES, PROTEASE INHIBITOR | DUPONT PHARMACEUTICALS COMPANY | 2002-07-02 | — | — | US | disclosed |