Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 4/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738327 | 0.89 | AKR1B1 (0.38) | MEN1KMT2ASMN1; SMN2IDO1GSK3B | |
| SCHEMBL7738267 | 0.78 | POLB (0.35) | TBXAS1CYP19A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL10544271 | 0.75 | NLRP3 (0.43) | SMN1; SMN2IDO1GSK3BLOXL2AKR1B1 | |
| SCHEMBL7740266 | 0.73 | ALDH1A1 (0.33) | TBXAS1CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6758059 | 0.73 | CYP19A1 (0.54) | TBXAS1CYP19A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6758056 | 0.71 | TAAR1 (0.51) | LOXL2 | |
| SCHEMBL7737870 | 0.66 | CYP19A1 (0.67) | TBXAS1CYP19A1IDO1POLBCYP11B1 | |
| SCHEMBL7740332 | 0.65 | AKR1B1 (0.38) | IDO1GSK3BLOXL2AKR1B1MIF | |
| SCHEMBL7277261 | 0.64 | ALOX15 (0.52) | TBXAS1CYP19A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7738275 | 0.62 | TAAR1 (0.35) | MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE37781-E1 | VIRICIDES, PROTEASE INHIBITOR | DUPONT PHARMACEUTICALS COMPANY | 2002-07-02 | — | — | US | disclosed |