SCHEMBL7740408

SCHEMBL7740408

O=P(O)(O)N(c1ccccc1)c1ccccc1-c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
HSD17B10 Q99714 2/20 0.36
HPGD P15428 1/20 0.36
BCL2L1 Q07817 1/20 0.36
HDAC4 P56524 1/20 0.36
HDAC2 Q92769 1/20 0.36
HDAC8 Q9BY41 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
GPR84 Q9NQS5 1/20 0.36
HTT P42858 1/20 0.35
BCAT2 O15382 1/20 0.35
CHRNB2 P17787 1/20 0.35
CHRNB4 P30926 1/20 0.35
CHRNA3 P32297 1/20 0.35
CHRNA4 P43681 1/20 0.35
TACR1 P25103 1/20 0.35
ACP3 P15309 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7740475 0.93 ALDH1A1 (0.34) ALDH1A1HSD17B10HPGDBCL2L1HDAC4
SCHEMBL2309806 0.78 MEN1 (0.48) ALDH1A1HPGDMEN1KMT2AHTT
SCHEMBL8530739 0.78 MEN1 (0.48) ALDH1A1HPGDMEN1KMT2AHTT
Phosphoric Acid SCHEMBL28441188 0.77 MEN1 (0.42) ALDH1A1HSD17B10HPGDBCL2L1HDAC4
SCHEMBL6748159 0.76 POLB (0.39) ALDH1A1HDAC2HDAC8HDAC6MEN1
Hydrochloric Acid SCHEMBL27627985 0.76 MEN1 (0.46) ALDH1A1HPGDMEN1KMT2AHTT
SCHEMBL11764058 0.74 SIGMAR1 (0.46) HDAC8ACP3CA2
SCHEMBL7734199 0.71 ALDH1A1 (0.41) ALDH1A1MEN1KMT2ACA2
SCHEMBL7742129 0.71 ESR2 (0.36) ALDH1A1MEN1KMT2ASMN1; SMN2GPR84
Phosphoric Acid SCHEMBL1281473 0.71 ALDH1A1 (0.52) ALDH1A1HSD17B10HPGDBCL2L1HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6414060-B1 ADDITION-CONDENSATION COPOLYMER ALBEMARLE CORPORATION 2002-07-02 US disclosed
EP-1067153-A1 Flame retardant polycarbonate-ABS polymer compositions ALBEMARLE CORPORATION (US) 2001-01-10 EP disclosed