Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | ACP3 | P15309 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9386229 | 0.81 | LMNA (0.39) | POLBACP3HTTKMT2AMEN1 | |
| SCHEMBL2309806 | 0.80 | MEN1 (0.48) | HTTKMT2AMEN1ALDH1A1CA2 | |
| SCHEMBL8530739 | 0.80 | MEN1 (0.48) | HTTKMT2AMEN1ALDH1A1CA2 | |
| Hydrochloric Acid SCHEMBL27627985 | 0.78 | MEN1 (0.46) | HTTKMT2AMEN1ALDH1A1CA2 | |
| SCHEMBL7740408 | 0.76 | ALDH1A1 (0.36) | ACP3HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL10881554 | 0.76 | SMN1; SMN2 (0.41) | POLBACP3SMN1; SMN2ALDH1A1CA2 | |
| SCHEMBL11764058 | 0.75 | SIGMAR1 (0.46) | ACP3CA2PTK2BHDAC8NPC1 | |
| Methane SCHEMBL10785614 | 0.75 | SMN1; SMN2 (0.39) | POLBACP3SMN1; SMN2ALDH1A1CA2 | |
| SCHEMBL7740475 | 0.74 | ALDH1A1 (0.34) | ACP3HTTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL5892 | 0.71 | HTT (0.44) | POLBHTTKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142946-A1 | Modified nucleosides and nucleotides and use thereof | CHATTOPADHYAYA JYOTI (SE) | 2004-07-22 | — | — | US | claimed |
| EP-1332150-A1 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES AND USE THEREOF | Chattopadhyaya, Jyoti (SE) | 2003-08-06 | — | — | EP | claimed |
| WO-2002038578-A1 | MODIFIED NUCLEOSIDES AND NUCLEOTIDES AND USE THEREOF | CHATTOPADHYAYA JYOTI (SE) | 2002-05-16 | — | — | WO | claimed |
| US-5721350-A | Deuterated nucleosides | CHATTOPADHYAYA JYOTI (SE) | 1998-02-24 | — | — | US | claimed |
| WO-1993025566-A1 | DEUTERATED NUCLEOSIDES | CHATTOPADHYAYA JYOTI (SE) | 1993-12-23 | — | — | WO | claimed |
| EP-0335409-B1 | Pyrimidine derivatives, processes for their production and herbicidal compositions containing them | KUMIAI CHEMICAL INDUSTRY CO (JP) | 1994-12-07 | — | — | EP | disclosed |
| US-4969949-A | NONPHYTOTOXIC | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1990-11-13 | — | — | US | disclosed |
| EP-0335409-A2 | Pyrimidine derivatives, processes for their production and herbicidal compositions containing them | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1989-10-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142946-A1 | Modified nucleosides and nucleotides and use thereof | RNASEH1, RNASEL, NSUN2 | POLB 215/4885ACP3 3518/4885HTT 2636/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.