SCHEMBL7740415

SCHEMBL7740415

Cc1ccccc1-c1ccccc1N(c1ccccc1C)P(=O)(O)O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 9/20 0.35
LMNA P02545 2/20 0.34
HSD17B1 P14061 1/20 0.34
CYP3A4 P08684 3/20 0.33
BRD4 O60885 1/20 0.33
TRPM8 Q7Z2W7 1/20 0.33
APAF1 O14727 1/20 0.33
NPC1 O15118 1/20 0.33
TDP2 O95551 1/20 0.33
NSD2 O96028 1/20 0.33
CYP1A2 P05177 1/20 0.33
MAPT P10636 1/20 0.33
CYP2C9 P11712 1/20 0.33
CYP2C19 P33261 1/20 0.33
CASP3 P42574 1/20 0.33
RAB9A P51151 1/20 0.33
BLM P54132 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SENP8 Q96LD8 1/20 0.33
NLRP3 Q96P20 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28562906 0.96 GPBAR1 (0.37) GPBAR1BRD4ACP3
SCHEMBL7740492 0.85 MYC (0.33) GPBAR1LMNAHSD17B1CYP3A4BRD4
SCHEMBL2847873 0.77 GPBAR1 (0.35) GPBAR1LMNAHSD17B1
SCHEMBL852429 0.69 ESR1 (0.35) GPBAR1LMNACYP3A4RAB9A
SCHEMBL15605366 0.69 TSHR (0.41) GPBAR1CYP3A4BRD4NPC1CYP1A2
SCHEMBL3965515 0.69 ALDH1A1 (0.44) GPBAR1LMNACYP3A4BRD4NPC1
Phosphoric Acid SCHEMBL28782897 0.68 TRPA1 (0.41) LMNACYP3A4BRD4NPC1CYP1A2
SCHEMBL7740475 0.68 ALDH1A1 (0.34) LMNASMN1; SMN2ACP3
SCHEMBL8365536 0.67 ALDH1A1 (0.39) CYP1A2MAPTACP3
SCHEMBL30169568 0.67 ACHE (0.64) CYP3A4BRD4NPC1CYP1A2CASP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112839949-A Cyclic phosphazene compound, flame retardant for resin, resin composition containing same, and molded article thereof 大塚化学株式会社 2021-05-25 CN disclosed
US-6414060-B1 ADDITION-CONDENSATION COPOLYMER ALBEMARLE CORPORATION 2002-07-02 US disclosed
EP-1067153-A1 Flame retardant polycarbonate-ABS polymer compositions ALBEMARLE CORPORATION (US) 2001-01-10 EP disclosed