Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 4/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.43 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746271 | 0.87 | TSHR (0.45) | TSHRSMN1; SMN2PTK2BRAB9ANPC1 | |
| SCHEMBL7745897 | 0.85 | RAB9A (0.46) | TSHRSMN1; SMN2PTK2BRAB9ATP53 | |
| SCHEMBL6480793 | 0.85 | CES1 (0.45) | TSHRPTK2BCES1BCHEKMT2A | |
| SCHEMBL7745462 | 0.83 | POLB (0.46) | CES1BCHEALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL7740562 | 0.83 | TSHR (0.57) | TSHRSMN1; SMN2TP53CES1BCHE | |
| SCHEMBL7745478 | 0.82 | GRM2 (0.41) | TSHRSMN1; SMN2PTK2BRAB9ANPC1 | |
| SCHEMBL7746299 | 0.81 | TSHR (0.40) | TSHRSMN1; SMN2PTK2BRAB9ANPC1 | |
| SCHEMBL7745936 | 0.80 | TSHR (0.41) | TSHRSMN1; SMN2PTK2BRAB9ANPC1 | |
| SCHEMBL7741406 | 0.77 | DRD2 (0.44) | TSHRSMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL7740984 | 0.76 | TBXA2R (0.38) | TSHRSMN1; SMN2RAB9ATP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |