Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | CES1 | P23141 | 5/20 | 0.45 |
| ▸ | BCHE | P06276 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | ALDH2 | P05091 | 2/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.44 |
| ▸ | TGM2 | P21980 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7745816 | 0.86 | HEXA (0.53) | POLBDRD2HTR6ALDH1A1TOP2A | |
| SCHEMBL7740562 | 0.84 | TSHR (0.57) | POLBCES1BCHEALDH1A1ALDH2 | |
| SCHEMBL7740965 | 0.83 | TSHR (0.49) | CES1BCHEALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL6480793 | 0.82 | CES1 (0.45) | CES1BCHEALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL7745897 | 0.79 | RAB9A (0.46) | POLBCES1ALDH1A1ALDH2ALDH3A1 | |
| SCHEMBL7745820 | 0.78 | POLB (0.41) | POLBALDH1A1TOP2ALMNAMAPT | |
| SCHEMBL7745883 | 0.76 | AGTR1 (0.42) | POLBALDH1A1LMNAMAPT | |
| SCHEMBL4205713 | 0.76 | DRD2 (0.72) | DRD2HTR6CES1BCHEALDH1A1 | |
| SCHEMBL7745712 | 0.76 | PKM (0.48) | POLBALDH1A1TOP2ALMNAHTR2A | |
| SCHEMBL7745904 | 0.75 | DRD2 (0.44) | POLBDRD2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |