Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | TRPV4 | Q9HBA0 | 15/20 | 0.35 |
| ▸ | ADK | P55263 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7210077 | 0.86 | HDAC6 (0.74) | HDAC6HSPA8ADORA3 | |
| SCHEMBL7210083 | 0.86 | HDAC6 (0.74) | HDAC6HSPA8ADORA3 | |
| SCHEMBL7116242 | 0.85 | HDAC6 (0.55) | HDAC6HSPA8ADORA3FBP1TRPV4 | |
| SCHEMBL7215020 | 0.84 | HDAC6 (0.74) | HDAC6HSPA8ADORA3FBP1TRPV4 | |
| SCHEMBL7215024 | 0.84 | HDAC6 (0.74) | HDAC6HSPA8ADORA3FBP1TRPV4 | |
| SCHEMBL10308324 | 0.84 | HDAC6 (0.74) | HDAC6HSPA8ADORA3FBP1TRPV4 | |
| SCHEMBL7114592 | 0.84 | HDAC6 (0.54) | HDAC6HSPA8ADORA3TRPV4 | |
| SCHEMBL7734525 | 0.82 | HDAC6 (0.57) | HDAC6HSPA8TRPV4ADK | |
| SCHEMBL7742258 | 0.82 | HDAC6 (0.57) | HDAC6HSPA8ADK | |
| SCHEMBL7734307 | 0.82 | HDAC6 (0.49) | HDAC6HSPA8ADORA3FBP1TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |