Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7734525 | 0.91 | HDAC6 (0.57) | HDAC6HSPA8MAPTHTTMEN1 | |
| SCHEMBL7215020 | 0.86 | HDAC6 (0.74) | HDAC6HSPA8ADK | |
| SCHEMBL10308324 | 0.86 | HDAC6 (0.74) | HDAC6HSPA8ADK | |
| SCHEMBL7215024 | 0.86 | HDAC6 (0.74) | HDAC6HSPA8ADK | |
| SCHEMBL7733484 | 0.84 | HDAC6 (0.49) | HDAC6HSPA8ADK | |
| SCHEMBL7114288 | 0.84 | HDAC6 (0.49) | HDAC6HSPA8HTR3A | |
| SCHEMBL7117206 | 0.83 | HDAC6 (0.48) | HDAC6MAPTNPSR1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7739904 | 0.83 | HDAC6 (0.63) | HDAC6HSPA8MAPTSMN1; SMN2 | |
| SCHEMBL7734303 | 0.82 | SLC15A1 (0.38) | HDAC6HSPA8MAPTMEN1KMT2A | |
| SCHEMBL7740697 | 0.82 | HDAC6 (0.54) | HDAC6HSPA8ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |