Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | HSPA8 | P11142 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 3/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.33 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7742258 | 0.91 | HDAC6 (0.57) | HDAC6HSPA8ADORA2BMEN1MAPT | |
| SCHEMBL10308324 | 0.86 | HDAC6 (0.74) | HDAC6HSPA8ADKTRPV4 | |
| SCHEMBL7215024 | 0.86 | HDAC6 (0.74) | HDAC6HSPA8ADKTRPV4 | |
| SCHEMBL7215020 | 0.86 | HDAC6 (0.74) | HDAC6HSPA8ADKTRPV4 | |
| SCHEMBL7734310 | 0.85 | HDAC6 (0.50) | HDAC6HSPA8MEN1KMT2AADK | |
| SCHEMBL7734332 | 0.85 | HDAC6 (0.50) | HDAC6HSPA8ADKTRPV4 | |
| SCHEMBL7114052 | 0.84 | HDAC6 (0.49) | HDAC6HSPA8MEN1KMT2ATRPV4 | |
| SCHEMBL7739904 | 0.83 | HDAC6 (0.63) | HDAC6HSPA8MAPTTRPV4 | |
| SCHEMBL7739913 | 0.82 | SLC15A1 (0.38) | HDAC6HSPA8ADORA2BKMT2AADK | |
| SCHEMBL7740697 | 0.82 | HDAC6 (0.54) | HDAC6HSPA8ADKTRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413938-B1 | HERPES VIRUS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-07-02 | — | — | US | disclosed |