SCHEMBL7740796

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL27557880	1.00	CYP3A4 (0.81)	CYP3A4ABCB1ABCC4ABCB11TACR2
	SCHEMBL9953067	0.90	CYP3A4 (0.65)	CYP3A4ABCB1ABCC4ABCB11TACR2
	Saquinavir SCHEMBL8584252	0.89	CYP3A4 (1.00)	CYP3A4ABCB1ABCC4ABCB11TACR2
	Saquinavir SCHEMBL13953012	0.89	CYP3A4 (1.00)	CYP3A4ABCB1ABCC4ABCB11TACR2
	Saquinavir SCHEMBL1976548	0.89	CYP3A4 (1.00)	CYP3A4ABCB1ABCC4ABCB11TACR2
	Saquinavir SCHEMBL8584255	0.89	CYP3A4 (1.00)	CYP3A4ABCB1ABCC4ABCB11TACR2
	Saquinavir SCHEMBL20451344	0.89	CYP3A4 (1.00)	CYP3A4ABCB1ABCC4ABCB11TACR2
	Saquinavir SCHEMBL6881	0.89	CYP3A4 (1.00)	CYP3A4ABCB1ABCC4ABCB11TACR2
	Saquinavir SCHEMBL21683360	0.89	CYP3A4 (1.00)	CYP3A4ABCB1ABCC4ABCB11TACR2
	Saquinavir SCHEMBL1176566	0.89	CYP3A4 (1.00)	CYP3A4ABCB1ABCC4ABCB11TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.