Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PDE5A | O76074 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747083 | 0.88 | KDM4E (0.52) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL3825708 | 0.80 | TSHR (0.57) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL6243676 | 0.78 | BCHE (0.49) | TSHRMAPK1APEX1CNR2 | |
| SCHEMBL3827074 | 0.77 | TSHR (0.56) | TSHRMAPK1MEN1KMT2ANPSR1 | |
| SCHEMBL6499070 | 0.76 | BCHE (0.48) | TSHRMAPK1CNR2 | |
| SCHEMBL3822957 | 0.76 | TSHR (0.49) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL3823382 | 0.75 | TSHR (0.56) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL7740951 | 0.75 | TSHR (0.56) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL7745627 | 0.75 | ALDH1A1 (0.63) | TSHRMAPK1ALDH1A1MEN1KMT2A | |
| SCHEMBL6246552 | 0.75 | BCHE (0.47) | KDM4ECNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |