Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 17/20 | 0.57 |
| ▸ | MTNR1B | P49286 | 17/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984866 | 0.84 | CYP1A2 (0.49) | MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL6634999 | 0.80 | MTNR1A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL4590905 | 0.78 | MTNR1A (0.63) | MTNR1AMTNR1B | |
| SCHEMBL5573010 | 0.76 | MTNR1A (0.60) | MTNR1AMTNR1B | |
| SCHEMBL10447564 | 0.76 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL7741708 | 0.73 | MTNR1B (0.66) | MTNR1AMTNR1B | |
| SCHEMBL3348647 | 0.73 | CYP1A2 (0.47) | MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL30618514 | 0.73 | CYP1A2 (0.47) | MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL13116633 | 0.73 | CYP1A2 (0.44) | MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL6633601 | 0.73 | MTNR1A (1.00) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1247528-C | Novel tricyclic compounds, preparation method and pharmaceutical compositions containing same | SIRVIR LAB (FR) | 2006-03-29 | — | — | CN | disclosed |
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |