Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | TDO2 | P48775 | 2/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.40 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.37 |
| ▸ | PER2 | O15055 | 1/20 | 0.36 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.36 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740431 | 0.78 | POLB (0.45) | GAAMAPTPOLBSMN1; SMN2PKM | |
| SCHEMBL4821940 | 0.74 | MAPT (0.53) | GAAMAPTPOLBSMN1; SMN2PKM | |
| SCHEMBL4824434 | 0.74 | MAPT (0.47) | GAAMAPTPOLBSMN1; SMN2PKM | |
| SCHEMBL5017658 | 0.74 | HDAC1 (0.47) | HDAC1HDAC3PRSS1HDAC2NCOR2 | |
| SCHEMBL4054487 | 0.74 | HDAC1 (0.44) | HDAC1HDAC3PRSS1HDAC2NCOR2 | |
| SCHEMBL2447012 | 0.74 | MAPT (0.44) | GAAMAPTPOLBSMN1; SMN2PKM | |
| SCHEMBL4081482 | 0.73 | ALDH1A1 (0.54) | GAAMAPTHDAC1HDAC3PRSS1 | |
| SCHEMBL30829688 | 0.73 | ALDH1A1 (0.54) | GAAMAPTHDAC1HDAC3PRSS1 | |
| SCHEMBL7740540 | 0.73 | HDAC1 (0.41) | HDAC1HDAC3PRSS1HDAC2NCOR2 | |
| SCHEMBL12943716 | 0.73 | PTGER4 (0.60) | GAAMAPTSMN1; SMN2HDAC1HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |