Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 6/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | FERMT2 | Q96AC1 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5017658 | 0.81 | HDAC1 (0.47) | HDAC1PRSS1HDAC3HDAC2NCOR2 | |
| SCHEMBL8334585 | 0.79 | PRSS1 (0.49) | HDAC1PRSS1HDAC3ALDH1A1NCOR2 | |
| SCHEMBL7746065 | 0.77 | NCF1 (0.44) | HDAC1PRSS1HDAC3ALDH1A1 | |
| SCHEMBL12943716 | 0.77 | PTGER4 (0.60) | HDAC1PRSS1HDAC3ALDH1A1HDAC2 | |
| SCHEMBL7740540 | 0.77 | HDAC1 (0.41) | HDAC1PRSS1HDAC3HDAC2NCOR2 | |
| SCHEMBL23963004 | 0.77 | HDAC1 (0.50) | HDAC1PRSS1HDAC3ALDH1A1HDAC2 | |
| SCHEMBL30829688 | 0.77 | ALDH1A1 (0.54) | HDAC1PRSS1HDAC3ALDH1A1HDAC2 | |
| SCHEMBL4081482 | 0.77 | ALDH1A1 (0.54) | HDAC1PRSS1HDAC3ALDH1A1HDAC2 | |
| SCHEMBL29126106 | 0.76 | HDAC1 (0.51) | HDAC1PRSS1HDAC3ALDH1A1HDAC2 | |
| Hydrochloric Acid SCHEMBL15158302 | 0.76 | PTGER4 (0.58) | HDAC1PRSS1HDAC3ALDH1A1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101600701-A | Arylsulfonamide derivatives and methods of use thereof | WYETH CORP (US) | 2009-12-09 | — | — | CN | disclosed |
| EP-2061776-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | Wyeth a Corporation of the State of Delaware (US) | 2009-05-27 | — | — | EP | disclosed |
| WO-2008073459-A1 | ARYL SULFAMIDE DERIVATIVES AND METHODS OF THEIR USE | WYETH (US) | 2008-06-19 | — | — | WO | disclosed |