Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.59 |
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7740592 | 0.85 | POLB (0.64) | KMT2AMEN1LMNAPOLBMAPT | |
| SCHEMBL3059715 | 0.80 | MEN1 (0.64) | KMT2AMEN1LMNAPOLBMAPT | |
| SCHEMBL102779 | 0.78 | MEN1 (0.77) | KMT2AMEN1LMNAPOLBMAPT | |
| SCHEMBL7740446 | 0.77 | SMN1; SMN2 (0.61) | KMT2AMEN1LMNAPOLBTSHR | |
| SCHEMBL3729168 | 0.76 | TSHR (0.76) | KMT2AMEN1LMNAPOLBMAPT | |
| SCHEMBL18148387 | 0.76 | RAB9A (0.64) | KMT2AMEN1LMNAMAPTRECQL | |
| SCHEMBL7741401 | 0.76 | MEN1 (0.59) | KMT2AMEN1LMNAPOLBMAPT | |
| SCHEMBL8365517 | 0.76 | LMNA (0.68) | KMT2AMEN1LMNAPOLBMAPT | |
| SCHEMBL4155796 | 0.76 | MEN1 (0.68) | KMT2AMEN1LMNAMAPTTSHR | |
| SCHEMBL31183018 | 0.76 | MEN1 (0.68) | KMT2AMEN1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |