SCHEMBL7741288

SCHEMBL7741288

CCCNC(=O)C(CCC(=O)NO)NC(=O)c1ccc(C#CCOC)cc1

nearest known ligand 0.48

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7741293 1.00 L3MBTL1 (0.44) L3MBTL1
SCHEMBL7735055 0.92
SCHEMBL7735052 0.92
SCHEMBL7742586 0.90 POLB (0.40)
SCHEMBL7742579 0.90 POLB (0.40)
SCHEMBL7734857 0.89 HDAC1 (0.39)
SCHEMBL7734853 0.89 HDAC1 (0.39)
SCHEMBL7740175 0.88 MMP8 (0.46) L3MBTL1
SCHEMBL7740171 0.88 MMP8 (0.46) L3MBTL1
SCHEMBL7740324 0.86 CCKBR (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6420427-B1 PREVENTION AND/OR TREATMENT OF RHEUMATOID DISEASES, ARTHROSTEITIS, UNUSUAL BONE RESORPTION, OSTEOPOROSIS, PERIODONTITIS, INTERSTITIAL NEPHRITIS, ARTERIOSCLEROSIS, PULMONARY EMPHYSEMA, CIRRHOSIS, CORNEA INJURY ONO PHARMACEUTICAL CO., LTD. (JP) 2002-07-16 US disclosed
EP-1024134-A1 AMINOBUTANOIC ACID DERIVATIVES ONO PHARMACEUTICAL CO., LTD. (JP) 2000-08-02 EP disclosed