SCHEMBL7741335

SCHEMBL7741335

Cc1ccc(S)cc1C.[LiH]

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
TDP1 Q9NUW8 4/20 0.36
TSHR P16473 2/20 0.36
PRSS1 P07477 1/20 0.36
PRSS2 P07478 1/20 0.36
PRSS3 P35030 1/20 0.36
LMNA P02545 1/20 0.36
ACHE P22303 1/20 0.35
POLB P06746 1/20 0.32
CES2 O00748 1/20 0.32
CES1 P23141 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ADRB1 P08588 1/20 0.31
CASP1 P29466 1/20 0.31
CYP1A2 P05177 1/20 0.30
IDO1 P14902 1/20 0.30
KDM4E B2RXH2 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL91378 0.97
Acetic Acid SCHEMBL9107179 0.83 CES2 (0.44) ALDH1A1TDP1LMNAPOLBCES2
SCHEMBL29767277 0.79
SCHEMBL330857 0.79
SCHEMBL29507711 0.77
SCHEMBL63648 0.77
SCHEMBL1158048 0.74 ALDH1A1 (0.41) ALDH1A1POLBSMN1; SMN2MAPT
SCHEMBL8417971 0.74 ALDH1A1 (0.41) ALDH1A1POLBSMN1; SMN2MAPT
SCHEMBL456165 0.72
SCHEMBL13681182 0.72 CYP1A2 (0.46) ALDH1A1TDP1TSHRLMNACYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6413677-B1 THIOCARBONATE ELECTROLYTE UBE INDUSTRIES, LTD. (JP) 2002-07-02 US disclosed