SCHEMBL7741433

SCHEMBL7741433

CSC(=O)C(=O)SC1CCCCC1

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.34
NPC1 O15118 3/20 0.34
RAB9A P51151 3/20 0.34
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
TSHR P16473 2/20 0.32
RECQL P46063 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
NPSR1 Q6W5P4 1/20 0.31
EPHX1 P07099 5/20 0.30
MAPT P10636 1/20 0.30
KDM4E B2RXH2 1/20 0.30
CYP3A4 P08684 1/20 0.30
EPHX2 P34913 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7741486 0.79 CES2 (0.35) ALDH1A1NPC1RAB9ACES2CES1
SCHEMBL17322712 0.76 CES2 (0.36) ALDH1A1NPC1RAB9ACES2CES1
SCHEMBL172020 0.76 CES2 (0.32) ALDH1A1NPC1RAB9ACES2CES1
SCHEMBL7742833 0.74 CES2 (0.35) ALDH1A1NPC1RAB9ACES2CES1
SCHEMBL2142264 0.73 CES2 (0.38) ALDH1A1NPC1RAB9ACES2CES1
SCHEMBL8789579 0.73 CES2 (0.38) ALDH1A1NPC1RAB9ACES2CES1
SCHEMBL8788775 0.73 CES2 (0.38) ALDH1A1NPC1RAB9ACES2CES1
SCHEMBL7742834 0.73 MGLL (0.34) ALDH1A1NPC1RAB9ACES2CES1
SCHEMBL7739914 0.73 EPHX1 (0.41) ALDH1A1NPC1RAB9ATSHRSMN1; SMN2
SCHEMBL3075371 0.72 CES2 (0.41) ALDH1A1NPC1RAB9ACES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6413677-B1 THIOCARBONATE ELECTROLYTE UBE INDUSTRIES, LTD. (JP) 2002-07-02 US disclosed