SCHEMBL7741486

SCHEMBL7741486

CSC(=O)SC1CCCCC1

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
RAB9A P51151 4/20 0.32
NPC1 O15118 3/20 0.32
ALDH1A1 P00352 3/20 0.32
MAPK1 P28482 1/20 0.31
EPHX1 P07099 5/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
MAPT P10636 1/20 0.31
KDM4E B2RXH2 1/20 0.31
CYP3A4 P08684 1/20 0.31
EPHX2 P34913 1/20 0.31
KMT2A Q03164 1/20 0.31
HDAC8 Q9BY41 1/20 0.30
HDAC6 Q9UBN7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3075371 0.85 CES2 (0.41) CES2CES1RAB9ANPC1ALDH1A1
SCHEMBL7741433 0.79 ALDH1A1 (0.34) CES2CES1RAB9ANPC1ALDH1A1
SCHEMBL2142264 0.75 CES2 (0.38) CES2CES1RAB9ANPC1ALDH1A1
SCHEMBL8788775 0.75 CES2 (0.38) CES2CES1RAB9ANPC1ALDH1A1
SCHEMBL8789579 0.75 CES2 (0.38) CES2CES1RAB9ANPC1ALDH1A1
SCHEMBL10922157 0.73 TDP1 (0.39) RAB9AALDH1A1EPHX1SMN1; SMN2KDM4E
SCHEMBL3777071 0.72 CES2 (0.39) CES2CES1RAB9ANPC1ALDH1A1
SCHEMBL11956974 0.72
SCHEMBL13789070 0.71 EPHX1 (0.38) EPHX1
SCHEMBL11595861 0.70 NPC1 (0.39) CES2CES1RAB9ANPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6413677-B1 THIOCARBONATE ELECTROLYTE UBE INDUSTRIES, LTD. (JP) 2002-07-02 US disclosed