Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746853 | 0.79 | MEN1 (0.41) | MEN1KMT2AUSP2L3MBTL1SMN1; SMN2 | |
| SCHEMBL7740722 | 0.77 | MEN1 (0.54) | MEN1KMT2AUSP2L3MBTL1SMN1; SMN2 | |
| SCHEMBL7745194 | 0.77 | SMN1; SMN2 (0.59) | MEN1KMT2ASMN1; SMN2TSHRPOLB | |
| SCHEMBL7740409 | 0.73 | MEN1 (0.42) | MEN1KMT2AUSP2L3MBTL1SMN1; SMN2 | |
| SCHEMBL13344490 | 0.70 | TSHR (0.58) | MEN1KMT2AL3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL3824637 | 0.70 | TSHR (0.48) | MEN1KMT2AUSP2L3MBTL1SMN1; SMN2 | |
| SCHEMBL7745952 | 0.70 | RAB9A (0.45) | MEN1KMT2AUSP2L3MBTL1SMN1; SMN2 | |
| SCHEMBL15416721 | 0.69 | KMT2A (0.56) | MEN1KMT2AUSP2L3MBTL1SMN1; SMN2 | |
| SCHEMBL15416397 | 0.69 | POLB (0.61) | MEN1KMT2AUSP2SMN1; SMN2TSHR | |
| SCHEMBL5858779 | 0.68 | SLC9A1 (0.46) | MEN1KMT2AUSP2L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |