SCHEMBL7741754

SCHEMBL7741754

CC(=O)c1ccc2c(c1)-c1ccccc1-2

nearest known ligand 0.85

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.85
PTPRC P08575 3/20 0.57
MAPT P10636 3/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
PDK2 Q15119 1/20 0.53
ALDH1A1 P00352 2/20 0.50
HPGD P15428 2/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NR1H2 P55055 1/20 0.49
NR1H3 Q13133 1/20 0.49
TTR P02766 1/20 0.48
HSD17B1 P14061 1/20 0.47
LMNA P02545 1/20 0.45
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
POLB P06746 1/20 0.44
CYP2A6 P11509 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8033807 0.93 S100A4 (0.73) S100A4PTPRCMAPTNPC1RAB9A
SCHEMBL9423385 0.92 S100A4 (0.93) S100A4PTPRCMAPTNPC1RAB9A
SCHEMBL2599394 0.92 S100A4 (1.00) S100A4PTPRCMAPTNPC1RAB9A
SCHEMBL6259661 0.88 S100A4 (0.93) S100A4PTPRCMAPTNPC1RAB9A
SCHEMBL31268599 0.88 S100A4 (0.86) S100A4PTPRCMAPTNPC1RAB9A
SCHEMBL8014885 0.88 S100A4 (0.86) S100A4PTPRCMAPTNPC1RAB9A
SCHEMBL28658029 0.86 S100A4 (0.66) S100A4PTPRCMAPTNPC1RAB9A
SCHEMBL16694449 0.86 S100A4 (0.65) S100A4PTPRCMAPTALDH1A1SMN1; SMN2
SCHEMBL10881228 0.85 S100A4 (0.82) S100A4PTPRCMAPTNPC1RAB9A
Dimethylamine SCHEMBL7241455 0.83 S100A4 (0.77) S100A4PTPRCMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5663030-A A PHENYL OR NORBORNANE DERIVATIVE AS AN ADDITIVE TO REDUCE HEAT AND ENERGY REQUIRED TO FUSE THE TONER AND TO REDUCE JAMMING OF THE EQUIPMENT XEROX CORPORATION (US) 1997-09-02 US claimed
US-4507462-A CROSSLINKING AMINOKETONE ETHERS POLYMER SCIENCE (US) 1985-03-26 US claimed
US-20170190842-A1 O-HYDROXY-FUNCTIONALIZED DIAMINES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE KING ABDULLAH UNIVERSITY OF SCIENCE AND TECHNOLOGY (SA) 2017-07-06 US disclosed
US-6420613-B1 CHEMICAL REDUCTION WITH TRICHLOROSILANE TOKUYAMA CORPORATION (JP) 2002-07-16 US disclosed
EP-1086941-A1 PROCESS FOR PREPARING REDUCTANTS OF UNSATURATED ORGANIC COMPOUNDS BY THE USE OF TRICHLOROSILANE AND REDUCING AGENTS TOKUYAMA CORPORATION (JP) 2001-03-28 EP disclosed
EP-0547162-B1 PHENOL TERMINATED DIESTER COMPOSITION AND CURABLE COMPOSITIONS CONTAINING SAME EXXON CHEMICAL PATENTS INC (US) 1999-03-03 EP disclosed
US-5334671-A Protective coating EXXON CHEMICAL PATENTS INC. (US) 1994-08-02 US disclosed
US-5326831-A COATINGS EXXON CHEMICAL PATENTS INC. (US) 1994-07-05 US disclosed
EP-0547162-A1 PHENOL TERMINATED DIESTER COMPOSITION AND CURABLE COMPOSITIONS CONTAINING SAME EXXON CHEMICAL PATENTS INC. (US) 1993-06-23 EP disclosed
US-5210155-A Coatings and paints; hardness, high impact strength, corrosion resistance, weatherproof, solvent resistance EXXON CHEMICAL PATENTS INC. (US) 1993-05-11 US disclosed
WO-1992003492-A1 PHENOL TERMINATED DIESTER COMPOSITION AND CURABLE COMPOSITIONS CONTAINING SAME EXXON CHEMICAL PATENTS INC. (US) 1992-03-05 WO disclosed
US-4507462-A CROSSLINKING AMINOKETONE ETHERS POLYMER SCIENCE (US) 1985-03-26 US disclosed
EP-0072180-A1 Low molecular weight aromatic polymers with biphenylene end groups POLYMER SCIENCES CORPORATION (US) 1983-02-16 EP disclosed
US-4269953-A Method of crosslinking aromatic thermoplastic polymers using a biphenylene terminated compound GENERAL DYNAMICS CORPORATION (US) 1981-05-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170190842-A1 O-HYDROXY-FUNCTIONALIZED DIAMINES, POLYIMIDES, METHODS OF MAKING EACH, AND METHODS OF USE ALKBH3, AOC1, PAM S100A4 2320/4885PTPRC 2330/4885MAPT 3676/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.