Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.52 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741764 | 0.88 | TSHR (0.52) | KDM4EALDH1A1TSHRMAPK1MEN1 | |
| SCHEMBL3825708 | 0.74 | TSHR (0.57) | KDM4EALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL7740559 | 0.74 | NOD2 (0.56) | KDM4EALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL3827074 | 0.74 | TSHR (0.56) | TSHRMAPK1MAPTHTTMEN1 | |
| SCHEMBL9049818 | 0.73 | KMT2A (0.59) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL7879899 | 0.72 | MEN1 (0.44) | TSHRMAPK1MAPTMEN1KMT2A | |
| SCHEMBL10487900 | 0.72 | MEN1 (0.72) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL3823382 | 0.72 | TSHR (0.56) | KDM4EALDH1A1TSHRHPGDMAPK1 | |
| SCHEMBL16696069 | 0.71 | TSHR (0.46) | KDM4EALDH1A1HSD17B10TSHRHPGD | |
| SCHEMBL7740507 | 0.71 | MAPK1 (0.68) | KDM4EALDH1A1TSHRMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |
| US-6774134-B2 | FOR THERAPY OF RESPIRATORY SYNCYTIAL VIRUS INFECTION | BRISTOL-MYERS SQUIBB COMPANY | 2004-08-10 | — | — | US | disclosed |