Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KAT2B | Q92831 | 2/20 | 0.70 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | GUCY1B2 | O75343 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | GUCY1A2 | P33402 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | GUCY1A1 | Q02108 | 1/20 | 0.56 |
| ▸ | GUCY1B1 | Q02153 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7120033 | 0.93 | CYP2D6 (0.66) | KAT2BCYP1A2CYP2D6KDM4EGUCY1B2 | |
| SCHEMBL13481257 | 0.83 | CNR2 (0.56) | KAT2BCYP1A2CYP2D6KDM4EGUCY1B2 | |
| SCHEMBL17571535 | 0.82 | KAT2B (1.00) | KAT2BCYP1A2CYP2D6KDM4EGUCY1B2 | |
| SCHEMBL9917397 | 0.79 | DRD1 (0.88) | KAT2BCYP1A2CYP2D6KDM4EGUCY1B2 | |
| SCHEMBL8013419 | 0.78 | HRH3 (0.74) | KAT2BCYP1A2CYP2D6KDM4EGUCY1B2 | |
| SCHEMBL9917492 | 0.76 | ADRA1A (0.60) | KAT2BCYP1A2CYP2D6KDM4EGUCY1B2 | |
| SCHEMBL8007454 | 0.74 | HRH3 (0.69) | KAT2BCYP1A2CYP2D6KDM4EGUCY1B2 | |
| SCHEMBL7737863 | 0.73 | CNR1 (0.51) | CYP1A2KDM4ECNR2CNR1HTT | |
| SCHEMBL7998369 | 0.72 | CYP2D6 (0.59) | KAT2BCYP1A2CYP2D6KDM4EGUCY1B2 | |
| Benzydamine SCHEMBL26172 | 0.72 | HRH3 (1.00) | KAT2BCYP1A2CYP2D6KDM4EGUCY1B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | HTR1A, HTR3B, HTR3A | KAT2B 3789/4885CYP1A2 588/4885CYP2D6 650/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.