Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 7/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6635580 | 0.86 | MTNR1A (0.52) | MTNR1AMTNR1B | |
| SCHEMBL25604626 | 0.83 | EPHX2 (0.54) | MTNR1AMTNR1BCYP1A2 | |
| SCHEMBL7735732 | 0.81 | MTNR1A (0.49) | MTNR1AMTNR1B | |
| SCHEMBL10617785 | 0.79 | MTNR1A (0.44) | MTNR1AMTNR1B | |
| SCHEMBL8410015 | 0.78 | MTNR1A (0.62) | MTNR1AMTNR1B | |
| SCHEMBL10616643 | 0.77 | ADRA1A (0.59) | MTNR1AMTNR1B | |
| Fumaric Acid SCHEMBL10618366 | 0.77 | CHRM2 (0.47) | MTNR1AMTNR1B | |
| Maleic Acid SCHEMBL10618362 | 0.77 | CHRM2 (0.47) | MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL10615473 | 0.76 | ADRA1A (0.57) | MTNR1AMTNR1B | |
| SCHEMBL6638097 | 0.75 | MTNR1A (0.67) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423870-B1 | ANTICOAGULANTS; CIRCADIAN RHYTHM DISORDERS; SLEEP DISORDERS | LES LABORATOIRES SERVIER (FR) | 2002-07-23 | — | — | US | disclosed |
| EP-0288477-A1 | 2,3-DIHYDRO-1H-PHENALENE-2-AMINO COMPOUNDS AS ANTI-PSYCHOTIC DRUGS | THE UPJOHN COMPANY (US) | 1988-11-02 | — | — | EP | disclosed |
| EP-0234113-A1 | 2,3-Dihydro-1H-phenalene-2-amino compounds as anti-psychotic drugs | THE UPJOHN COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |
| WO-1987004153-A1 | 2,3-DIHYDRO-1H-PHENALENE-2-AMINO COMPOUNDS AS ANTI-PSYCHOTIC DRUGS | THE UPJOHN COMPANY (US) | 1987-07-16 | — | — | WO | disclosed |