Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 3/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.54 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL10615473 | 0.98 | ADRA1A (0.57) | ADRA1ADRD2DRD3MTNR1AMTNR1B | |
| SCHEMBL6634360 | 0.81 | MTNR1A (0.44) | MTNR1AMTNR1B | |
| SCHEMBL385443 | 0.80 | DRD2 (0.73) | ADRA1ADRD2DRD3 | |
| SCHEMBL31324598 | 0.80 | DRD2 (0.73) | ADRA1ADRD2DRD3 | |
| SCHEMBL6635819 | 0.80 | MTNR1B (0.54) | ADRA1AMTNR1AMTNR1B | |
| SCHEMBL10615302 | 0.79 | CHRM2 (0.57) | DRD2DRD3 | |
| SCHEMBL6634046 | 0.79 | MTNR1A (0.44) | MTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL1786250 | 0.79 | DRD2 (0.71) | ADRA1ADRD2DRD3 | |
| Hydrochloric Acid SCHEMBL10617539 | 0.78 | CHRM2 (0.56) | DRD2DRD3 | |
| SCHEMBL7741778 | 0.77 | MTNR1A (0.49) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0288477-A1 | 2,3-DIHYDRO-1H-PHENALENE-2-AMINO COMPOUNDS AS ANTI-PSYCHOTIC DRUGS | THE UPJOHN COMPANY (US) | 1988-11-02 | — | — | EP | disclosed |
| EP-0234113-A1 | 2,3-Dihydro-1H-phenalene-2-amino compounds as anti-psychotic drugs | THE UPJOHN COMPANY (US) | 1987-09-02 | — | — | EP | disclosed |
| WO-1987004153-A1 | 2,3-DIHYDRO-1H-PHENALENE-2-AMINO COMPOUNDS AS ANTI-PSYCHOTIC DRUGS | THE UPJOHN COMPANY (US) | 1987-07-16 | — | — | WO | disclosed |