Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 4/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.59 |
| ▸ | RECQL | P46063 | 3/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | USP2 | O75604 | 3/20 | 0.59 |
| ▸ | APEX1 | P27695 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 2/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741940 | 0.87 | MAPT (0.56) | MEN1POLBMAPTKMT2ARECQL | |
| SCHEMBL7741931 | 0.76 | MEN1 (0.55) | MEN1POLBKMT2ATDP1THRB | |
| SCHEMBL5004075 | 0.72 | MAPT (0.56) | MEN1POLBMAPTKMT2ARECQL | |
| SCHEMBL6805692 | 0.68 | TSHR (0.49) | MEN1POLBMAPTKMT2ARECQL | |
| SCHEMBL11157478 | 0.67 | MAPT (0.61) | MEN1POLBMAPTKMT2ARECQL | |
| SCHEMBL23009248 | 0.66 | KDM4E (0.63) | MEN1POLBMAPTKMT2ARECQL | |
| SCHEMBL2115613 | 0.66 | MAPT (1.00) | MEN1POLBMAPTKMT2ARECQL | |
| SCHEMBL7746359 | 0.65 | MEN1 (0.38) | MEN1MAPTKMT2ATDP1KDM4E | |
| SCHEMBL7746976 | 0.65 | MAPT (0.55) | MEN1POLBMAPTKMT2ARECQL | |
| SCHEMBL14938712 | 0.64 | ALDH1A1 (0.68) | POLBMAPTKMT2ATDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001027087-A2 | PROCESS FOR MAKING BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY (US) | 2001-04-19 | — | — | WO | disclosed |