Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | APEX1 | P27695 | 2/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.55 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.55 |
| ▸ | HBB | P68871 | 1/20 | 0.55 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7741940 | 0.71 | MAPT (0.56) | MAPTMEN1POLBKMT2AAPEX1 | |
| SCHEMBL2115613 | 0.71 | MAPT (1.00) | MAPTMEN1POLBKMT2AAPEX1 | |
| SCHEMBL23009248 | 0.65 | KDM4E (0.63) | MAPTMEN1POLBKMT2AAPEX1 | |
| SCHEMBL11362739 | 0.65 | TSHR (0.59) | MAPTMEN1POLBKMT2AAPEX1 | |
| SCHEMBL7741927 | 0.65 | MEN1 (0.59) | MAPTMEN1POLBKMT2AAPEX1 | |
| SCHEMBL7553199 | 0.63 | ALDH1A1 (0.56) | MAPTPOLBL3MBTL1TSHRALDH1A1 | |
| SCHEMBL5004075 | 0.63 | MAPT (0.56) | MAPTMEN1POLBKMT2AAPEX1 | |
| SCHEMBL2795967 | 0.63 | ALDH1A1 (0.54) | MAPTMEN1POLBKMT2AAPEX1 | |
| SCHEMBL15679881 | 0.63 | TSHR (0.43) | MAPTMEN1POLBKMT2AAPEX1 | |
| SCHEMBL16277156 | 0.62 | SIGMAR1 (0.50) | MEN1KMT2ATDP1KDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001027087-A2 | PROCESS FOR MAKING BOC-PROTECTED 3-AMINOHYDANTOINS/THIOHYDANTOINS AND 3-AMINODIHYDROURACILS/DIHYDROTHIOURACILS | THE PROCTER & GAMBLE COMPANY (US) | 2001-04-19 | — | — | WO | disclosed |