Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 13/20 | 0.53 |
| ▸ | MAPK13 | O15264 | 6/20 | 0.53 |
| ▸ | MAPK12 | P53778 | 6/20 | 0.53 |
| ▸ | MAPK11 | Q15759 | 6/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.53 |
| ▸ | GCGR | P47871 | 2/20 | 0.53 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | RET | P07949 | 1/20 | 0.53 |
| ▸ | PRKACA | P17612 | 1/20 | 0.53 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.53 |
| ▸ | MATK | P42679 | 1/20 | 0.53 |
| ▸ | FRK | P42685 | 1/20 | 0.53 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.53 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.53 |
| ▸ | GSK3A | P49840 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11338005 | 0.78 | NOX1 (0.49) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL8112645 | 0.75 | ALOX5 (0.59) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL7090083 | 0.74 | MAPK14 (0.65) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL9648774 | 0.74 | KDM4E (0.70) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL7089146 | 0.73 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL7090769 | 0.71 | MAPK14 (0.61) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL7085449 | 0.70 | MAPK14 (0.60) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL8805296 | 0.70 | PTGS2 (0.56) | MAPK14MAPK11ALOX5CSNK1A1CSNK1D | |
| SCHEMBL22170123 | 0.69 | MAPK11 (1.00) | MAPK14MAPK13MAPK12MAPK11ALOX5 | |
| SCHEMBL1388020 | 0.69 | MAPK11 (1.00) | MAPK14MAPK13MAPK12MAPK11ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6426360-B1 | ANTIARTHRITIC AGENTS | G D SEARLE & CO. | 2002-07-30 | — | — | US | disclosed |