Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7742857 | 1.00 | L3MBTL1 (0.51) | L3MBTL1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL10805172 | 0.87 | SLC1A3 (0.49) | ALDH1A1TSHRLTA4HSLC1A3SLC1A1 | |
| SCHEMBL6447987 | 0.82 | SLC1A1 (0.59) | TSHRLTA4HSLC1A3SLC1A1LMNA | |
| SCHEMBL7271113 | 0.82 | SLC1A1 (0.59) | TSHRLTA4HSLC1A3SLC1A1LMNA | |
| SCHEMBL13955400 | 0.81 | ALDH1A1 (0.57) | L3MBTL1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL17244713 | 0.79 | DPP8 (0.61) | L3MBTL1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL7302361 | 0.79 | SLC1A3 (0.42) | ALDH1A1TSHRCTSLCTSSCTSK | |
| SCHEMBL7151534 | 0.78 | SYK (0.50) | CTSLCTSSCTSKMAPTLTA4H | |
| SCHEMBL4729999 | 0.77 | TSHR (0.55) | L3MBTL1ALDH1A1CYP3A4TSHRMAPK1 | |
| SCHEMBL28204578 | 0.77 | KMT2A (0.58) | L3MBTL1ALDH1A1CYP3A4TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420166-B2 | REACTING AN N-PROTECTED ASPARAGINE ESTER WITH A PROTEASE IN AQUEOUS SOLUTION AT PH OF 6.0 TO 7.5 AND AN ORGANIC SOLVENT, AND EXTRACTING THE N-PROTECTED-D-ASPARAGINE ESTER; CHEMICAL INTERMEDIATES TO ANTIBACTERIAL COMPOUNDS | BASOLEA PHARMACEUTICA AG (CH) | 2002-07-16 | — | — | US | disclosed |
| US-20010049127-A1 | Process for the preparation of D-asparagine derivatives | HOFFMANN-LA ROCHE INC. | 2001-12-06 | — | — | US | disclosed |
| EP-1148140-A1 | Process for the preparation of D-asparagine derivatives | Basilea Pharmaceutica AG (CH) | 2001-10-24 | — | — | EP | disclosed |