Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | FPR1 | P21462 | 3/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 8/20 | 0.39 |
| ▸ | CNR2 | P34972 | 7/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150009 | 0.79 | ALDH1A1 (0.60) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL7152017 | 0.71 | ALDH1A1 (0.60) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL19335348 | 0.67 | ELANE (0.49) | ALDH1A1LMNAELANE | |
| SCHEMBL7690827 | 0.66 | CNR2 (0.57) | KMT2AMEN1KDM4EALDH1A1GAA | |
| SCHEMBL23393760 | 0.65 | ELANE (0.56) | ELANE | |
| SCHEMBL18826237 | 0.65 | ELANE (0.49) | ELANE | |
| SCHEMBL9925703 | 0.64 | ELANE (0.64) | ELANE | |
| SCHEMBL4708959 | 0.63 | KMT2A (1.00) | KMT2AMEN1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL32660897 | 0.63 | ELANE (0.49) | ELANECNR1CNR2 | |
| SCHEMBL13267872 | 0.63 | GAPDH (0.64) | KMT2AMEN1KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420571-B2 | Methods for preparing antiviral calanolide compounds | SARAWAK MEDICHEM PHARMACEUTICALS, INC. | 2002-07-16 | — | — | US | disclosed |