Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 9/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 8/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAP1LC3B | Q9GZQ8 | 2/20 | 0.40 |
| ▸ | MAP1LC3A | Q9H492 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | POLQ | O75417 | 1/20 | 0.39 |
| ▸ | ALB | P02768 | 1/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938077 | 0.87 | HSP90AB1 (0.46) | HSP90AB1HSP90AA1KDM4EKMT2AMAP1LC3B | |
| SCHEMBL6938071 | 0.87 | HSP90AB1 (0.46) | HSP90AB1HSP90AA1KDM4EKMT2AMAP1LC3B | |
| SCHEMBL6156108 | 0.81 | HSP90AB1 (0.49) | HSP90AB1HSP90AA1KDM4EKMT2AMAP1LC3B | |
| SCHEMBL8444987 | 0.81 | HSP90AB1 (0.49) | HSP90AB1HSP90AA1KDM4EKMT2AMAP1LC3B | |
| SCHEMBL6867189 | 0.77 | KDM4E (0.51) | HSP90AB1HSP90AA1KDM4EKMT2AMAP1LC3B | |
| SCHEMBL6867185 | 0.77 | KDM4E (0.51) | HSP90AB1HSP90AA1KDM4EKMT2AMAP1LC3B | |
| SCHEMBL7195888 | 0.76 | MAP1LC3B (0.42) | HSP90AB1HSP90AA1KDM4EMAP1LC3BMAP1LC3A | |
| SCHEMBL6160624 | 0.76 | HSP90AB1 (0.47) | HSP90AB1HSP90AA1KDM4EKMT2AMAP1LC3B | |
| SCHEMBL7189371 | 0.73 | HSP90AB1 (0.62) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ | |
| SCHEMBL7189370 | 0.73 | HSP90AB1 (0.62) | HSP90AB1HSP90AA1MAP1LC3BMAP1LC3APOLQ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420538-B1 | COMPOUND FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS | AVENTIS PHARMA S.A. (FR) | 2002-07-16 | — | — | US | disclosed |