Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPG | P29372 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747654 | 1.00 | MPG (0.40) | MPGHRH2HRH1CYP2D6FNTA | |
| SCHEMBL7747674 | 0.77 | FNTA (0.45) | CYP2D6FNTAFNTBHRH3 | |
| SCHEMBL7747199 | 0.71 | MPG (0.40) | MPGHRH2HRH1CYP2D6FNTA | |
| SCHEMBL7127275 | 0.71 | FNTA (0.36) | HRH1FNTAFNTBHRH3 | |
| SCHEMBL7128886 | 0.71 | FNTA (0.36) | HRH1FNTAFNTBHRH3 | |
| SCHEMBL7516922 | 0.68 | ALDH1A1 (0.46) | FNTAFNTBKDM4EGAATSHR | |
| SCHEMBL4111392 | 0.68 | SIGMAR1 (0.53) | MPGCYP2D6FNTAFNTBSIGMAR1 | |
| SCHEMBL2750851 | 0.67 | HRH3 (0.62) | MPGHRH1KDM4EHRH3 | |
| SCHEMBL27864314 | 0.66 | HRH3 (0.58) | MPGHRH1HRH3 | |
| SCHEMBL31010330 | 0.66 | HRH3 (0.63) | MPGHRH1CYP2D6HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001022963-A1 | METHOD OF PREVENTING OSTEOPOROSIS | MERCK & CO., INC. (US) | 2001-04-05 | — | — | WO | claimed |
| WO-2001022963-A1 | METHOD OF PREVENTING OSTEOPOROSIS | MERCK & CO., INC. (US) | 2001-04-05 | — | — | WO | disclosed |